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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC1 All Species: 25.15
Human Site: T1281 Identified Species: 50.3
UniProt: P33527 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33527 NP_004987.2 1531 171561 T1281 A P W Q I Q E T A P P S S W P
Chimpanzee Pan troglodytes XP_001145351 1247 137800 N1013 V G R V E F R N Y C L R Y R E
Rhesus Macaque Macaca mulatta XP_001094709 1612 178491 S1362 A P W V V E G S R P P K G W P
Dog Lupus familis XP_548204 1523 168842 S1273 A P W V V E G S R P P A G W P
Cat Felis silvestris
Mouse Mus musculus O35379 1528 171166 T1278 A P W Q I Q E T A P P S T W P
Rat Rattus norvegicus Q8CG09 1532 171475 T1282 A S W Q I Q E T A P P S T W P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517193 1537 172363 T1287 A P W Q I E E T A P A P D W P
Chicken Gallus gallus Q5F364 1525 170953 T1275 A E W S I E E T A P A S T W P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341895 1518 169232 S1268 A E W K L E N S N L P P G W P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995704 1548 173512 K1297 P W E L E Q D K N K P K N W P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42093 1623 182111 N1230 A P P V I E N N R P P P G W P
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 H1260 A P L I V E G H R P P K E W P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.5 54.1 56.6 N.A. 88.1 87.4 N.A. 84.2 77.6 N.A. 70.5 N.A. 51.2 N.A. N.A. N.A.
Protein Similarity: 100 80.1 71 74.1 N.A. 94.7 93.8 N.A. 91.7 89.2 N.A. 83.2 N.A. 68.5 N.A. N.A. N.A.
P-Site Identity: 100 0 46.6 46.6 N.A. 93.3 86.6 N.A. 73.3 66.6 N.A. 33.3 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 0 66.6 73.3 N.A. 100 93.3 N.A. 80 80 N.A. 60 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.2 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 51.8 59.3 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 0 0 0 0 0 0 0 42 0 17 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % D
% Glu: 0 17 9 0 17 59 42 0 0 0 0 0 9 0 9 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 25 0 0 0 0 0 34 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 50 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 9 0 9 0 25 0 0 0 % K
% Leu: 0 0 9 9 9 0 0 0 0 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 17 17 17 0 0 0 9 0 0 % N
% Pro: 9 59 9 0 0 0 0 0 0 75 75 25 0 0 92 % P
% Gln: 0 0 0 34 0 34 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 9 0 34 0 0 9 0 9 0 % R
% Ser: 0 9 0 9 0 0 0 25 0 0 0 34 9 0 0 % S
% Thr: 0 0 0 0 0 0 0 42 0 0 0 0 25 0 0 % T
% Val: 9 0 0 34 25 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 9 67 0 0 0 0 0 0 0 0 0 0 92 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _